Article
FOXP3 Allelic Variants and Haplotype Structures Are Associated with Aggressive Breast Cancer Subtypes.
Disease markers - 1 Jan 2017
Banin Hirata Bruna Karina, Losi Guembarovski Roberta, Vitiello Glauco Akelinghton Freire, Guembarovski Alda Losi, Brajão de Oliveira Karen, Watanabe Maria Angelica Ehara
Abstract excerpt
FOXP3 genetic polymorphisms have been associated with cancer development and prognosis. In this context, the present study aimed to evaluate the g.10403A>G (rs2232365) polymorphisms and g.8048A>C (rs3761548), in aggressive breast cancer (BC) subtypes, including, Luminal B HER2+ (LB), HER2-enriched (HER2+), and triple-negative (TN). Polymerase chain reaction followed by enzymatic restriction was performed to...
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