Article
FOXP3 transcription factor: a candidate marker for susceptibility and prognosis in triple negative breast cancer.
BioMed research international - 1 Jan 2014
Lopes Leandra Fiori, Guembarovski Roberta Losi, Guembarovski Alda Losi, Kishima Marina Okuyama, Campos Clodoaldo Zago, Oda Julie Massayo Maeda, Ariza Carolina Batista, de Oliveira Karen Brajão, Borelli Sueli Donizete, Watanabe Maria Angelica Ehara
Abstract excerpt
Triple negative breast cancer (TNBC) is a relevant subgroup of neoplasia which presents negative phenotype of estrogen and progesterone receptors and has no overexpression of the human epidermal growth factor 2 (HER2). FOXP3 (forkhead transcription factor 3) is a marker of regulatory T cells (Tregs), whose expression may be increased in tumor cells. This study aimed to investigate a polymorphism (rs3761548) and...
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