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Article

Steroid 5-alpha-reductase type 2 (SRD5A2) gene V89L polymorphism and hypospadias risk: A meta-analysis.

Journal of pediatric urology - 1 Dec 2017

Zhang K, Li Y, Mao Y, Ma M

Abstract excerpt

BACKGROUND: Hypospadias is a common congenital malformation in males, in which the urethral orifice is found on the ventral side of the penis as a result of incomplete fusion of urethral folds. The etiology of hypospadias is poorly understood, and may be multifactorial, including genetic, endocrine and environmental factors. The steroid 5-alpha-reductase type 2 (SRD5A2) gene, which is mainly expressed in the...

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PMID: 28713005
DOI: 10.1016/j.jpurol.2017.05.022

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