Article
Novel data analysis method for multicolour flow cytometry links variability of multiple markers on single cells to a clinical phenotype.
Scientific reports - 14 Jul 2017
Tinnevelt Gerjen H, Kokla Marietta, Hilvering Bart, van Staveren Selma, Folcarelli Rita, Xue Luzheng, Bloem Andries C, Koenderman Leo, Buydens Lutgarde M C, Jansen Jeroen J
Abstract excerpt
Multicolour Flow Cytometry (MFC) produces multidimensional analytical data on the quantitative expression of multiple markers on single cells. This data contains invaluable biomedical information on (1) the marker expressions per cell, (2) the variation in such expression across cells, (3) the variability of cell marker expression across samples that (4) may vary systematically between cells collected from donors...
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