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Article

The dental phenotype of hairless dogs with FOXI3 haploinsufficiency.

Scientific reports - 14 Jul 2017

Kupczik Kornelius, Cagan Alexander, Brauer Silke, Fischer Martin S

Abstract excerpt

Hairless dog breeds show a form of ectodermal dysplasia characterised by a lack of hair and abnormal tooth morphology. This has been attributed to a semi-dominant 7-base-pair duplication in the first exon of the forkhead box I3 gene (FOXI3) shared by all three breeds. Here, we identified this FOXI3 variant in a historical museum sample of pedigreed hairless dog skulls by using ancient DNA extraction and present...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28710361
DOI: 10.1038/s41598-017-05764-5
PMCID: PMC5511229

Genes

FOXI3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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