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Article

A mutation in hairless dogs implicates FOXI3 in ectodermal development.

Science (New York, N.Y.) - 12 Sept 2008

Drögemüller Cord, Karlsson Elinor K, Hytönen Marjo K, Perloski Michele, Dolf Gaudenz, Sainio Kirsi, Lohi Hannes, Lindblad-Toh Kerstin, Leeb Tosso

Abstract excerpt

Mexican and Peruvian hairless dogs and Chinese crested dogs are characterized by missing hair and teeth, a phenotype termed canine ectodermal dysplasia (CED). CED is inherited as a monogenic autosomal semidominant trait. With genomewide association analysis we mapped the CED mutation to a 102-kil...

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Source

Identifiers

PMID: 18787161
DOI: 10.1126/science.1162525

Genes

FOXI3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18787161-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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