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Article

Naked but not Hairless: the pitfalls of analyses of molecular adaptation based on few genome sequence comparisons.

Genome biology and evolution - 20 Feb 2015

Delsuc Frédéric, Tilak Marie-Ka

Abstract excerpt

The naked mole-rat (Heterocephalus glaber) is the only rodent species that naturally lacks fur. Genome sequencing of this atypical rodent species recently shed light on a number of its morphological and physiological adaptations. More specifically, its hairless phenotype has been traced back to a single amino acid change (C397W) in the hair growth associated (HR) protein (or Hairless). By considering the...

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PMID: 25714745
DOI: 10.1093/gbe/evv036
PMCID: PMC5322551

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Source receipt: pubmed, retrieved 7 Sept 2026.

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