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Animal models of the placenta accreta spectrum: current status and further perspectives

8 May 2023

Abstract excerpt

Placenta accreta spectrum disorder (PAS) is a kind of disease of placentation defined as abnormal trophoblast invasion of part or all of the placenta into the myometrium, even penetrating the uterus. Decidual deficiency, abnormal vascular remodeling in the maternal-fetal interface, and excessive invasion by extravillous trophoblast (EVT) cells contribute to its onset. However, the mechanisms and signaling...

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PMID: 37223034
DOI: 10.3389/fendo.2023.1118168

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