Tracking Adventitial Fibroblast Contribution to Disease: A Review of Current Methods to Identify Resident Fibroblasts.

doi:10.1161/ATVBAHA.117.308199

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Article

Tracking Adventitial Fibroblast Contribution to Disease: A Review of Current Methods to Identify Resident Fibroblasts.

Arteriosclerosis, thrombosis, and vascular biology - 1 Sept 2017

Kuwabara Jill T, Tallquist Michelle D

Abstract excerpt

Cells present in the adventitia, or outermost layer of the blood vessel, contribute to the progression of vascular diseases, such as atherosclerosis, hypertension, and aortic dissection. The adventitial fibroblast of the aorta is the prototypic perivascular fibroblast, but the adventitia is composed of multiple distinct cell populations. Therefore, methods for uniquely identifying the fibroblast are critical for...

Topics

Adventitia
Animals
Biomarkers
Cardiovascular Diseases
Cell Lineage
Fibroblasts
Genotype
Humans
Mice, Transgenic
Phenotype

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Identifiers

PMID: 28705796
DOI: 10.1161/ATVBAHA.117.308199
PMCID: PMC5656451

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