Article
The adventitia: a dynamic interface containing resident progenitor cells.
Arteriosclerosis, thrombosis, and vascular biology - 1 Jul 2011
Majesky Mark W, Dong Xiu Rong, Hoglund Virginia, Mahoney William M, Daum Guenter
Abstract excerpt
Conventional views of the tunica adventitia as a poorly organized layer of vessel wall composed of fibroblasts, connective tissue, and perivascular nerves are undergoing revision. Recent studies suggest that the adventitia has properties of a stem/progenitor cell niche in the artery wall that may be poised to respond to arterial injury. It is also a major site of immune surveillance and inflammatory cell...
Topics
- Animals
- Cell Communication
- Connective Tissue
- Humans
- Inflammation Mediators
- Phenotype
- Signal Transduction
- Stem Cell Niche
- Stem Cells
- Vascular Diseases