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Article

Genetic variants of PTGS2, TXA2R and TXAS1 are associated with carotid plaque vulnerability, platelet activation and TXA2 levels in ischemic stroke patients.

PloS one - 1 Jan 2017

Yi Xingyang, Lin Jing, Luo Hua, Wang Chun, Liu Yingying

Abstract excerpt

Eicosanoids may play a role in ischemic stroke. However, the associations of variants in cyclooxygenase (COX) pathway genes and interaction among these variants with carotid plaque vulnerability are not fully understood. In present study, twelve variants in COX pathway genes were examined using matrix-assisted laser desorption ionization time-of-flight mass spectrometry method in 396 patients with ischemic stroke...

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Source

Open in PubMed Open full text

Identifiers

PMID: 28704403
DOI: 10.1371/journal.pone.0180704
PMCID: PMC5507514

Genes

PTGS2
PTGIS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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