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A Case of Decreased Susceptibility to Ceftriaxone in Neisseria gonorrhoeae in the Absence of a Mosaic Penicillin-Binding Protein 2 (penA) Allele.

Sexually transmitted diseases - 1 Aug 2017

Abrams A Jeanine, Kirkcaldy Robert D, Pettus Kevin, Fox Jan L, Kubin Grace, Trees David L

Abstract excerpt

We report a case of Neisseria gonorrhoeae with a non-mosaic penA allele that exhibited decreased susceptibility to extended-spectrum cephalosporins, including a ceftriaxone minimum inhibitory concentration of 0.5 μg/mL. An analysis of resistance determinants suggested that the observed phenotype might have resulted from the combined effects of mutations in multiple genes.

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Identifiers

PMID: 28703729
DOI: 10.1097/OLQ.0000000000000645
PMCID: PMC6932624

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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