Article
Association and expression of the antigen-processing gene PSMB8, coding for low-molecular-mass protease 7, with vitiligo in North India: case-control study.
The British journal of dermatology - 1 Feb 2018
Dani P, Patnaik N, Singh A, Jaiswal A, Agrawal B, Kumar A A, Varkhande S R, Sharma A, Vaish U, Ghosh P, Sharma V K, Sharma P, Verma G, Kar H K, Gupta S, Natarajan V T, Gokhale R S, Rani R
Abstract excerpt
BACKGROUND: Vitiligo is a multifactorial, autoimmune, depigmenting disorder of the skin where aberrant presentation of autoantigens may have a role. OBJECTIVES: To study the association of two antigen-processing genes, PSMB8 and PSMB9, with vitiligo. METHODS: In total 1320 cases of vitiligo (1050 generalized and 270 localized) and 752 healthy controls were studied for the PSMB9 exon 3 G/A single-nucleotide...
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