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Article

Analysis of the heat shock protein 70 (HSP70) genetic variants in nonsegmental vitiligo patients.

International journal of dermatology - 1 Feb 2023

Ochoa-Ramírez Luis Antonio, Díaz-Camacho Sylvia Paz, Mellado-Corrales Samantha Nohemí, Muñoz-Estrada Víctor Fernando, Ríos-Tostado Juan José, Sánchez-Zazueta Jorge Guillermo, Velarde-Félix Jesús Salvador

Abstract excerpt

BACKGROUND: Vitiligo is an autoimmune disease that courses with skin depigmentation because of the destruction of melanocytes. Vitiliginous melanocyte is prone to damage because of oxidative stress which activates cellular stress response and the release of heat shock proteins such as HSP70 promoting immune activation against the melanocyte. Variants in HSP70 genes (HSPA) might alter their expression and thus...

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Identifiers

PMID: 36345598
DOI: 10.1111/ijd.16487

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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