Article
Identification of FBXL4 as a Metastasis Associated Gene in Prostate Cancer.
Scientific reports - 11 Jul 2017
Stankiewicz Elzbieta, Mao Xueying, Mangham D Chas, Xu Lei, Yeste-Velasco Marc, Fisher Gabrielle, North Bernard, Chaplin Tracy, Young Bryan, Wang Yuqin, Kaur Bansal Jasmin, Kudahetti Sakunthala, Spencer Lucy, Foster Christopher S, Møller Henrik, Scardino Peter, Oliver R Tim, Shamash Jonathan, Cuzick Jack, Cooper Colin S, Berney Daniel M, Lu Yong-Jie
Abstract excerpt
Prostate cancer is the most common cancer among western men, with a significant mortality and morbidity reported for advanced metastatic disease. Current understanding of metastatic disease is limited due to difficulty of sampling as prostate cancer mainly metastasizes to bone. By analysing prostate cancer bone metastases using high density microarrays, we found a common genomic copy number loss at 6q16.1-16.2,...
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