<scp>LRP</scp>5 knockdown: effect on prostate cancer invasion growth and skeletal metastasis <i>in vitro</i> and <i>in vivo</i>

Abstract excerpt

Prostate cancer (PCa) is a common hormone-dependent malignancy associated with the development of skeletal metastases. This is due to the increased expression of a number of growth factors, cytokines, and proteases which collectively drive the metastatic cascade in general and increased propensity to develop skeletal metastasis in particular. While a number of signaling pathways have been implicated in PCa...

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