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Article

A DAB2IP genotype: sex interaction is associated with abdominal aortic aneurysm expansion.

Journal of investigative medicine : the official publication of the American Federation for Clinical Research - 1 Oct 2017

Ye Zi, Austin Erin, Schaid Daniel J, Bailey Kent R, Pellikka Patricia A, Kullo Iftikhar J

Abstract excerpt

A faster expansion rate of abdominal aortic aneurysm (AAA) increases the risk of rupture. Women are at higher risk of rupture than men, but the mechanisms underlying this increased risk are unknown. We investigated whether genetic variants that influence susceptibility for AAA (CDKN2A-2B, SORT1, DAB2IP, LRP1 and LDLR) are associated with AAA expansion and whether these associations differ by sex in 650 patients...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 28698188
DOI: 10.1136/jim-2016-000404

Genes

SORT1
LDLR
LRP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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