Article
10 Years of GWAS Discovery: Biology, Function, and Translation.
American journal of human genetics - 6 Jul 2017
Visscher Peter M, Wray Naomi R, Zhang Qian, Sklar Pamela, McCarthy Mark I, Brown Matthew A, Yang Jian
Abstract excerpt
Application of the experimental design of genome-wide association studies (GWASs) is now 10 years old (young), and here we review the remarkable range of discoveries it has facilitated in population and complex-trait genetics, the biology of diseases, and translation toward new therapeutics. We predict the likely discoveries in the next 10 years, when GWASs will be based on millions of samples with array data...
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