Article
Outer membrane vesicles blebbing contributes to B. vulgatus mpk-mediated immune response silencing.
Gut microbes - 2 Jan 2018
Maerz Jan Kevin, Steimle Alex, Lange Anna, Bender Annika, Fehrenbacher Birgit, Frick Julia-Stefanie
Abstract excerpt
The Gram negative intestinal symbiont Bacteroides vulgatus mpk is able to prevent from induction of colonic inflammation in Rag1-/- mice and promotes immune balance in Il2-/- mice. These inflammation-silencing effects are associated with B. vulgatus mpk-mediated induction of semi-mature dendritic cells, especially in the colonic lamina propria (cLP). However the beneficial interaction of bacteria with host immune...
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