Article
HIV-1 genetic diversity and primary drug resistance mutations before large-scale access to antiretroviral therapy, Republic of Congo.
BMC research notes - 5 Jul 2017
Niama Fabien Roch, Vidal Nicole, Diop-Ndiaye Halimatou, Nguimbi Etienne, Ahombo Gabriel, Diakabana Philippe, Bayonne Kombo Édith Sophie, Mayengue Pembe Issamou, Kobawila Simon-Charles, Parra Henri Joseph, Toure-Kane Coumba
Abstract excerpt
BACKGROUND: In this work, we investigated the genetic diversity of HIV-1 and the presence of mutations conferring antiretroviral drug resistance in 50 drug-naïve infected persons in the Republic of Congo (RoC). Samples were obtained before large-scale access to HAART in 2002 and 2004. METHODS: To assess the HIV-1 genetic recombination, the sequencing of the pol gene encoding a protease and partial reverse...
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