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Article

HIV type 1 pol gene diversity and antiretroviral drug resistance mutations in the Democratic Republic of Congo (DRC).

AIDS research and human retroviruses - 1 Feb 2006

Vidal N, Mulanga C, Bazepeo S Edidi, Mwamba J Kasali, Tshimpaka J, Kashi M, Mama N, Valéa D, Delaporte E, Lepira F, Peeters M

Abstract excerpt

To study recombination and the natural polymorphism in pol of HIV-1 strains in the Democratic Republic of Congo (DRC) we sequenced the protease and RT genes for 70 HIV-1 strains previously characterized in the env V3-V5 region from a sentinel surveillance study in 2002. For 41 of the 70 (58.6%) strains, the same subtype/ CRF designations were observed in pol and env. Twenty-three (32.9%) of 70 pol sequences were...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 16478404
DOI: 10.1089/aid.2006.22.202

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