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Article

Multiple roles of RARRES1 in prostate cancer: Autophagy induction and angiogenesis inhibition.

PloS one - 1 Jan 2017

Roy Arpita, Ramalinga Malathi, Kim Okjin J, Chijioke Juliet, Lynch Solomon, Byers Stephen, Kumar Deepak

Abstract excerpt

BACKGROUND: Prostate cancer (PCa) poses a major health concern in men worldwide. Retinoic Acid Receptor Responder (RARRES1)/ Tazarotene-induced gene-1 (TIG-1) is a putative tumor suppressor gene that exerts its tumor suppressor function via unknown mechanisms. Epigenetic silencing of RARRES1 leads to its loss in several types of cancer, including PCa. Determining the molecular mechanisms that mediate the tumor...

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Source

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Identifiers

PMID: 28678839
DOI: 10.1371/journal.pone.0180344
PMCID: PMC5498036

Genes

RARRES1
SIRT1
ATG3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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