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Article

Impact of ABCB1, ABCG2, and CYP3A5 polymorphisms on plasma trough concentrations of apixaban in Japanese patients with atrial fibrillation.

Pharmacogenetics and genomics - 1 Sept 2017

Ueshima Satoshi, Hira Daiki, Fujii Ryo, Kimura Yuuma, Tomitsuka Chiho, Yamane Takuya, Tabuchi Yohei, Ozawa Tomoya, Itoh Hideki, Horie Minoru, Terada Tomohiro, Katsura Toshiya

Abstract excerpt

OBJECTIVES: During anticoagulant therapy, major bleeding is one of the most severe adverse effects. This study aimed to evaluate the relationships between ABCB1, ABCG2, and CYP3A5 polymorphisms and plasma trough concentrations of apixaban, a direct inhibitor of coagulation factor X. PATIENTS AND METHODS: A total of 70 plasma concentrations of apixaban from 44 Japanese patients with atrial fibrillation were...

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Share to ATP Binding Cassette Transporter, Subfamily G, Member 2

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 28678049
DOI: 10.1097/FPC.0000000000000294

Genes

ABCG2
ABCB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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