Childhood adversity and DNA methylation of genes involved in the hypothalamus–pituitary–adrenal axis and immune system: Whole-genome and candidate-gene associations

Abstract excerpt

In recent years, translational research involving humans and animals has uncovered biological and physiological pathways that explain associations between early adverse circumstances and long-term mental and physical health outcomes. In this article, we summarize the human and animal literature demonstrating that epigenetic alterations in key biological systems, the hypothalamus-pituitary-adrenal axis and immune...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Birth, Development, and Health
• Share to Early Childhood Education and Development
• Share to Stress Responses and Cortisol