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Article

miRNome landscape analysis reveals a 30 miRNA core in retinoblastoma

1 Jul 2017

Abstract excerpt

BACKGROUND: miRNAs exert their effect through a negative regulatory mechanism silencing expression upon hybridizing to their target mRNA, and have a prominent position in the control of many cellular processes including carcinogenesis. Previous miRNA studies on retinoblastoma (Rb) have been limited to specific miRNAs reported in other tumors or to medium density arrays. Here we report expression analysis of the...

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PMID: 28668075
DOI: 10.1186/s12885-017-3421-3

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