Article
The genomic landscape of retinoblastoma: a review.
Clinical & experimental ophthalmology - 1 Jan 2000
Thériault Brigitte L, Dimaras Helen, Gallie Brenda L, Corson Timothy W
Abstract excerpt
Retinoblastoma is a paediatric ocular tumour that continues to reveal much about the genetic basis of cancer development. Study of genomic aberrations in retinoblastoma tumours has exposed important mechanisms of cancer development and identified oncogenes and tumour suppressors that offer potential points of therapeutic intervention. The recent development of next-generation genomic technologies has allowed...
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