Article
Hopping into a hot seat: Role of DNA structural features on IS5-mediated gene activation and inactivation under stress.
PloS one - 1 Jan 2017
Humayun M Zafri, Zhang Zhongge, Butcher Anna M, Moshayedi Aref, Saier Milton H
Abstract excerpt
Insertion sequence elements (IS elements) are proposed to play major roles in shaping the genetic and phenotypic landscapes of prokaryotic cells. Recent evidence has raised the possibility that environmental stress conditions increase IS hopping into new sites, and often such hopping has the phenotypic effect of relieving the stress. Although stress-induced targeted mutations have been reported for a number of E....
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