Article
Ly6Chigh Monocytes Oscillate in the Heart During Homeostasis and After Myocardial Infarction-Brief Report.
Arteriosclerosis, thrombosis, and vascular biology - 1 Sept 2017
Schloss Maximilian J, Hilby Michael, Nitz Katrin, Guillamat Prats Raquel, Ferraro Bartolo, Leoni Giovanna, Soehnlein Oliver, Kessler Thorsten, He Wenyan, Luckow Bruno, Horckmans Michael, Weber Christian, Duchene Johan, Steffens Sabine
Abstract excerpt
OBJECTIVE: Circadian regulation of neutrophil homeostasis affects myocardial infarction (MI) healing. It is unknown whether diurnal variations of monocyte counts exist in the heart and whether this affects their cardiac infiltration in response to MI. APPROACH AND RESULTS: Murine blood and organs were harvested at distinct times of day and analyzed by flow cytometry. Ly6Chigh monocyte surface expression levels of...
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