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Article

Next generation immunohistochemistry: Emerging substitutes to genetic testing?

Seminars in diagnostic pathology - 1 May 2018

Andrici Juliana, Gill Anthony J, Hornick Jason L

Abstract excerpt

The identification of at-risk kindreds facilitates screening and risk reduction strategies for patients with hereditary cancer predisposition syndromes. Recently, immunohistochemistry (IHC) has emerged as a cost-effective strategy for detecting or inferring the presence of mutations in both tumors and the germline of patients presenting with tumors associated with hereditary cancer predisposition syndromes. In...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28662997
DOI: 10.1053/j.semdp.2017.05.004

Genes

BAP1
FAP
SDHB

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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