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The Human Microbiome and the Missing Heritability Problem

12 Jun 2017

Abstract excerpt

The "missing heritability" problem states that genetic variants in Genome-Wide Association Studies (GWAS) cannot completely explain the heritability of complex traits. Traditionally, the heritability of a phenotype is measured through familial studies using twins, siblings and other close relatives, making assumptions on the genetic similarities between them. When this heritability is compared to the one obtained...

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PMID: 28659968
DOI: 10.3389/fgene.2017.00080

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