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Evidence for Rapid Oxidative Phosphorylation and Lactate Fermentation in Motile Human Sperm by Hyperpolarized 13C Magnetic Resonance Spectroscopy

22 Jun 2017

Abstract excerpt

Abstract Poor sperm motility is a common cause of male infertility for which there are no empirical therapies. Sperm motility is powered by adenosine triphosphate but the relative importance of lactate fermentation and Oxidative Phosphorylation (OxPhos) is debated. To study the relationship between energy metabolism and sperm motility we used dissolution Dynamic Nuclear Polarization (dDNP) for the first time to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 28659585
DOI: 10.1038/s41598-017-04146-1

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