Article
Sperm meet the elevated energy demands to attain fertilization competence by increasing flux through aldolase
2025-04-10
Abstract excerpt
Prior to ejaculation, sperm are stored in the epididymis in a ‘resting’ metabolic state. Upon ejaculation, sperm must alter their metabolism to generate the energy needed to support the motility and maturation process known as capacitation to reach and fertilize the oocyte. How sperm regulate the capacitation-induced increase in carbon flux is unknown. Here, we use 13 C stable isotope labeling to follow glucose m...
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Identifiers and source
- Literature Corpus work
- d022ec52-77a5-57c6-8385-443995a29c74
- DOI
- 10.1101/2025.04.09.647926