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Metabolomics analysis of human spermatozoa reveals impaired metabolic pathways in asthenozoospermia

24 Jul 2024

Abstract excerpt

BACKGROUND: Infertility is a major health issue, affecting 15% of reproductive-age couples with male factors contributing to 50% of cases. Asthenozoospermia (AS), or low sperm motility, is a common cause of male infertility with complex aetiology, involving genetic and metabolic alterations, inflammation and oxidative stress. However, the molecular mechanisms behind low motility are unclear. In this study, we...

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PMID: 39046266
DOI: 10.1111/eci.14289

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