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Integrative proteomics and bioinformatic prediction enable a high-confidence apicoplast proteome in malaria parasites

13 Sept 2018

Abstract excerpt

Malaria parasites (Plasmodium spp.) and related apicomplexan pathogens contain a nonphotosynthetic plastid called the apicoplast. Derived from an unusual secondary eukaryote-eukaryote endosymbiosis, the apicoplast is a fascinating organelle whose function and biogenesis rely on a complex amalgamation of bacterial and algal pathways. Because these pathways are distinct from the human host, the apicoplast is an...

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PMID: 30212465
DOI: 10.1371/journal.pbio.2005895

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