Article
Genetic and phenotypic overlap of specific obsessive-compulsive and attention-deficit/hyperactive subtypes with Tourette syndrome.
Psychological medicine - 1 Jan 2018
Hirschtritt M E, Darrow S M, Illmann C, Osiecki L, Grados M, Sandor P, Dion Y, King R A, Pauls D, Budman C L, Cath D C, Greenberg E, Lyon G J, Yu D, McGrath L M, McMahon W M, Lee P C, Delucchi K L, Scharf J M, Mathews C A
Abstract excerpt
BACKGROUND: The unique phenotypic and genetic aspects of obsessive-compulsive (OCD) and attention-deficit/hyperactivity disorder (ADHD) among individuals with Tourette syndrome (TS) are not well characterized. Here, we examine symptom patterns and heritability of OCD and ADHD in TS families. METHOD: OCD and ADHD symptom patterns were examined in TS patients and their family members (N = 3494) using exploratory...
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