Identification of Two Heritable Cross-Disorder Endophenotypes for Tourette Syndrome.

doi:10.1176/appi.ajp.2016.16020240

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Article

Identification of Two Heritable Cross-Disorder Endophenotypes for Tourette Syndrome.

The American journal of psychiatry - 1 Apr 2017

Darrow Sabrina M, Hirschtritt Matthew E, Davis Lea K, Illmann Cornelia, Osiecki Lisa, Grados Marco, Sandor Paul, Dion Yves, King Robert, Pauls David, Budman Cathy L, Cath Danielle C, Greenberg Erica, Lyon Gholson J, Yu Dongmei, McGrath Lauren M, McMahon William M, Lee Paul C, Delucchi Kevin L, Scharf Jeremiah M, Mathews Carol A

Abstract excerpt

OBJECTIVE: Phenotypic heterogeneity in Tourette syndrome is partly due to complex genetic relationships among Tourette syndrome, obsessive-compulsive disorder (OCD), and attention deficit hyperactivity disorder (ADHD). Identifying symptom-based endophenotypes across diagnoses may aid gene-finding efforts. METHOD: Assessments for Tourette syndrome, OCD, and ADHD symptoms were conducted in a discovery sample of...

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Identifiers

PMID: 27809572
DOI: 10.1176/appi.ajp.2016.16020240
PMCID: PMC5378637

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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