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Article

Cyclin-dependent kinase 9 is a novel specific molecular target in adult T-cell leukemia/lymphoma

23 Jun 2017

Abstract excerpt

cells from healthy volunteers (n = 5) were 0.535, 0.30, and 0.36 μM, respectively. Next, NOG mice were used as recipients of tumor cells from an ATL patient. BAY 1143572-treated ATL-bearing mice (once daily 12.5 mg/kg oral application) demonstrated significantly decreased ATL cell infiltration of the liver and bone marrow, as well as decreased human soluble interleukin-2 receptor levels in serum (reflecting the...

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PMID: 28646117
DOI: 10.1182/blood-2016-09-741983

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