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Article

Adipose tissue macrophages develop from bone marrow–independent progenitors in Xenopus laevis and mouse

22 Jun 2017

Abstract excerpt

Abstract ATMs have a metabolic impact in mammals as they contribute to metabolically harmful AT inflammation. The control of the ATM number may have therapeutic potential; however, information on ATM ontogeny is scarce. Whereas it is thought that ATMs develop from circulating monocytes, various tissue-resident Mϕs are capable of self-renewal and develop from BM-independent progenitors without a monocyte...

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PMID: 28642277
DOI: 10.1189/jlb.1a0317-082rr

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