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Article

Association between B‑Myb proto‑oncogene and the development of malignant tumors (Review)

4 Jan 2021

Abstract excerpt

B‑Myb is a critical transcription factor in regulating cell cycle. Dysregulated expression of B‑Myb promotes tumor formation and development. B‑Myb is a proto‑oncogene ubiquitously expressed in proliferating cells, which maintains normal cell cycle progression. It participates in cell apoptosis, tumorigenesis and aging. In addition, B‑Myb is overexpressed in several malignant tumors, including breast cancer, lung...

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PMID: 33552284
DOI: 10.3892/ol.2021.12427

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