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Article

Influenza A Virus Coinfection through Transmission Can Support High Levels of Reassortment.

Journal of virology - 1 Aug 2015

Tao Hui, Li Lian, White Maria C, Steel John, Lowen Anice C

Abstract excerpt

UNLABELLED: The reassortment of gene segments between influenza viruses increases genomic diversity and plays an important role in viral evolution. We have shown previously that this process is highly efficient within a coinfected cell and, given synchronous coinfection at moderate or high doses, can give rise to ~60 to 70% of progeny shed from an animal host. Conversely, reassortment in vivo can be rendered...

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Identifiers

PMID: 26041285
DOI: 10.1128/JVI.01162-15
PMCID: PMC4524221

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