Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Effects of Fungicides on Human 3β-Hydroxysteroid Dehydrogenase 1 and Aromatase in Human Placental Cell Line JEG-3

1 Jan 2017

Abstract excerpt

Placenta secretes a large amount of progesterone and estradiol, which are critical for maintaining pregnancy. In human placenta, 3β-hydroxysteroid dehydrogenase 1 (HSD3B1) catalyzes pregnenolone to form progesterone, and aromatase (CYP19A1) catalyzes testosterone into estradiol. Fungicides display antifungal activities and are widely used to prevent fungal infections in agricultural plants. These chemicals...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Estrogen and related hormone effects
Share to Hormonal Regulation and Hypertension
Share to Pharmacogenetics and Drug Metabolism

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 28637041
DOI: 10.1159/000475531

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Effects of Fungicides on Human 3β-Hydroxysteroid Dehydrogenase 1 and Aromatase in Human Placental Cell Line JEG-3PMID 28637041Read ↗

Triazole fungicide tebuconazole disrupts human placental trophoblast cell functionsSemantic proximity Read ↗

Transcriptomic changes upon epoxiconazole exposure in a human stem cell-based model of developmental toxicitySemantic proximity Read ↗

Prothioconazole exposure disrupts oocyte maturation and fertilization by inducing mitochondrial dysfunction and apoptosis in miceSemantic proximity Read ↗

Useful functions of microbial metabolites.Semantic proximity Read ↗

Effect of azoxystrobin on the physiology, morphology, and sclerotial formation of Rhizoctonia solani from tobaccoSemantic proximity Read ↗

Teratogenic effects of two antifungal triazoles, triadimefon and triadimenol, on Xenopus laevis development: Craniofacial defectsSemantic proximity Read ↗

Hormones and the Resistance of Women to ParacoccidioidomycosisSemantic proximity Read ↗

Chemical Diversity of Ketosteroids as Potential Therapeutic AgentsSemantic proximity Read ↗

Discovery of new vascular disrupting agents based on evolutionarily conserved drug action, pesticide resistance mutations, and humanized yeast.Semantic proximity Read ↗

Developmental effects of an environmental antiandrogen: the fungicide vinclozolin alters sex differentiation of the male rat.Semantic proximity Read ↗

In vitro toxicological effects of estrogenic mycotoxins on human placental cells: Structure activity relationshipsSemantic proximity Read ↗

Mutation breeding of high 4-androstene-3,17-dione-producing Mycobacterium neoaurum ZADF-4 by atmospheric and room temperature plasma treatment.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.