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Article

CMV induces expansion of highly polyfunctional CD4+ T cell subset coexpressing CD57 and CD154.

Journal of leukocyte biology - 1 Feb 2017

Pera Alejandra, Vasudev Anusha, Tan Crystal, Kared Hassen, Solana Rafael, Larbi Anis

Abstract excerpt

CD4+ T cells are essential for human CMV infection control. CMV-specific CD4+ T cells possess antiviral functions and participate in anti-CMV humoral/cellular responses. In the elderly, CMV infection impairs immunity to other viruses and has been traditionally associated with T cell senescence; however, recent results suggest that, in younger people, CMV confers immune protection against other pathogens...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 27566833
DOI: 10.1189/jlb.4A0316-112R

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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