Article
RNase II regulates RNase PH and is essential for cell survival during starvation and stationary phase.
RNA (New York, N.Y.) - 1 Sept 2017
Sulthana Shaheen, Quesada Ernesto, Deutscher Murray P
Abstract excerpt
RNase II is the most active exoribonuclease in Escherichia coli cell extracts. Yet, its removal appears to have no deleterious effect on growing cells. Here, we show that RNase II is required for cell survival during prolonged stationary phase and upon starvation. The absence of RNase II leads to greatly increased rRNA degradation and to the accumulation of rRNA fragments, both of which lead to a decline in cell...
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