Article
Novel Zinc Finger Protein Gene 469 (ZNF469) Variants in Advanced Keratoconus.
Current eye research - 1 Oct 2017
Yildiz Elvin, Bardak Handan, Gunay Murat, Bardak Yavuz, Imamoglu Serhat, Ozbas Halil, Bagci Ozkan
Abstract excerpt
PURPOSE: Common polymorphic variants upstream of Zinc finger protein gene 469 (ZNF469) have been associated with central corneal thickness. Rare ZNF469 variants have been shown in keratoconus patients. The aim of the current study was to investigate the frequency of ZNF 469 gene variants in rapidly progressive advance keratoconus patients who underwent corneal transplant surgery by the age of 30, compared to...
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