Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification of seven novel ZNF469 mutations in keratoconus patients in a Han Chinese population.

Molecular vision - 1 Jan 2017

Yu Xiaoning, Chen Binbin, Zhang Xin, Shentu Xingchao

Abstract excerpt

PURPOSE: To test for the potential presence of novel mutations in the zinc finger protein (ZNF469) gene in patients with sporadic keratoconus (KC) from a Han Chinese population. METHODS: Fifty-three patients with primary KC, 30 patients with high myopia (HM), and 100 unrelated population-matched healthy controls without any ocular or systemic disorders, all of Han Chinese ethnicity, were recruited. Blood samples...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adolescent
Share to Asian People
Share to Child

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Mutational Analysis

Share to Ethnicity

Share to Keratoconus

Share to Transcription Factors

Share to Young Adult

Source

Open in PubMed Open full text

Identifiers

PMID: 28484309
PMCID: PMC5410165

Genes

DOCK9

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification of seven novel ZNF469 mutations in keratoconus patients in a Han Chinese population.PMID 28484309Read ↗

Evidence against ZNF469 being causative for keratoconus in Polish patients.Semantic proximity Read ↗

Mutations in the zinc finger protein gene, ZNF469, contribute to the pathogenesis of keratoconus.Semantic proximity Read ↗

Novel Zinc Finger Protein Gene 469 (ZNF469) Variants in Advanced Keratoconus.Semantic proximity Read ↗

Novel mutations identified in the Chinese Han population with keratoconus by next-generation sequencingSemantic proximity Read ↗

Brittle cornea syndrome ZNF469 mutation carrier phenotype and segregation analysis of rare ZNF469 variants in familial keratoconus.Semantic proximity Read ↗

Analysis of candidate variants in a Chinese family with monozygotic twins with keratoconus: a case report.Semantic proximity Read ↗

Rare, Potentially Pathogenic Variants in ZNF469 Are Not Enriched in Keratoconus in a Large Australian Cohort of European Descent.Semantic proximity Read ↗

Enrichment of pathogenic alleles in the brittle cornea gene, ZNF469, in keratoconus.Semantic proximity Read ↗

Whole exome sequencing highlights variants in association with Keratoconus in Jordanian families.Semantic proximity Read ↗

New ZNF644 mutations identified in patients with high myopia.Semantic proximity Read ↗

Whole-exome sequencing screening for candidate genes and variants associated with primary sporadic keratoconus in Chinese patients.Semantic proximity Read ↗

Exome sequencing identification of susceptibility genes in Chinese patients with keratoconus.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.