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[Genetic and Clinical Characteristics of A Family with Combined PROC and PROS1 Genetic Variants].

Zhongguo shi yan xue ye xue za zhi - 1 Apr 2021

Wang Xing, Sheng Guang-Ying, Zhang Wei, Zhao Yun-Xiao, Xia Li-Jun, Jiang Miao

Abstract excerpt

OBJECTIVE: To test the anticoagulation functions, perform the genetic diagnosis and analyze the clinical characteristics in a family with combined heterozygous genetic variants of PROC and PROS1. METHODS: Peripheral blood was collected from all the family members. Hematological phenotypes and activity of anticoagulant factors were analyzed. Target genes were amplified by PCR from DNA isolated from peripheral...

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Heterozygote
Mutation
Protein C
Protein S
Risk Factors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Venous Thromboembolism

Venous Thrombosis

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PMID: 33812436
DOI: 10.19746/j.cnki.issn.1009-2137.2021.02.045

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