Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Overexpression of RASD1 inhibits glioma cell migration/invasion and inactivates the AKT/mTOR signaling pathway

5 Jun 2017

Abstract excerpt

The RAS signaling pathway is hyperactive in malignant glioma due to overexpression and/or increased activity. A previous study identified that RASD1, a member of the RAS superfamily of small G-proteins, is a significantly dysregulated gene in oligodendroglial tumors that responded to chemotherapy. However, the role and mechanism of RASD1 in the progression of human glioma remain largely unknown. In the present...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Caveolin-1 and cellular processes
Share to Ferroptosis and cancer prognosis
Share to Glioma Diagnosis and Treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 28600528
DOI: 10.1038/s41598-017-03612-0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Overexpression of RASD1 inhibits glioma cell migration/invasion and inactivates the AKT/mTOR signaling pathwayPMID 28600528Read ↗

IDH1 mutation activates mTOR signaling pathway, promotes cell proliferation and invasion in glioma cells.Semantic proximity Read ↗

Decreased expression of miR-410-3p correlates with poor prognosis and tumorigenesis in human gliomaSemantic proximity Read ↗

Genome-wide transcriptional analysis of BRD4-regulated genes and pathways in human glioma U251 cellsSemantic proximity Read ↗

PHLDA1 promotes glioblastoma cell growth via sustaining the activation state of RasSemantic proximity Read ↗

Smarcd1 Inhibits the Malignant Phenotypes of Human Glioblastoma Cells via Crosstalk with Notch1.Semantic proximity Read ↗

Long non-coding RNA GAS5, by up-regulating PRC2 and targeting the promoter methylation of miR-424, suppresses multiple malignant phenotypes of glioma.Semantic proximity Read ↗

The novel chromatin architectural regulator SND1 promotes glioma proliferation and invasion and predicts the prognosis of patientsSemantic proximity Read ↗

Up-regulation of MARVEL domain-containing protein 1 (MARVELD1) accelerated the malignant phenotype of glioma cancer cells via mediating JAK/STAT signaling pathway.Semantic proximity Read ↗

CircRNA CDR1as Promotes Glioma Progression by Regulating miR-514a-3p/STAT3 Signaling PathwaySemantic proximity Read ↗

Co-overexpression of RIOK1 and AKT1 as a prognostic risk factor in gliomaSemantic proximity Read ↗

MicroRNA-199a-3p suppresses glioma cell proliferation by regulating the AKT/mTOR signaling pathwaySemantic proximity Read ↗

Targeting Ras-RAF-ERK and its Interactive Pathways as a Novel Therapy for Malignant GliomasSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.