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Article

Profiles of Long Noncoding RNAs in Human Naive and Memory T Cells

10 Jun 2017

Abstract excerpt

Abstract We employed whole-genome RNA-sequencing to profile mRNAs and both annotated and novel long noncoding RNAs (lncRNAs) in human naive, central memory, and effector memory CD4+ T cells. Loci transcribing both lineage-specific annotated and novel lncRNA are adjacent to lineage-specific protein-coding genes in the genome. Lineage-specific novel lncRNA loci are transcribed from lineage-specific typical- and...

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PMID: 28600289
DOI: 10.4049/jimmunol.1700232

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