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Article

Expression of novel long noncoding RNAs defines virus-specific effector and memory CD8+ T cells

8 Jan 2019

Abstract excerpt

Abstract In response to viral infection, CD8+ T cells undergo expansion and differentiate into distinct classes of effector cells. After clearance of the virus, a small population of long-lived memory cells persists. Comprehensive studies have defined the protein-coding transcriptional changes associated with this process. Here we expand on this prior work by performing RNA-sequencing to identify changes in long...

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PMID: 30643116
DOI: 10.1038/s41467-018-07956-7

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