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Article

Role of AXL in invasion and drug resistance of colon and breast cancer cells and its association with p53 alterations.

World journal of gastroenterology - 21 May 2017

Abdel-Rahman Wael M, Al-Khayyal Noura A, Nair Vidhya A, Aravind S R, Saber-Ayad Maha

Abstract excerpt

AIM: To characterize AXL receptor tyrosine kinase (AXL) expression in relationship to tumor protein P53 (TP53 gene, p53 protein) and its role in tumor invasion and response to therapy. METHODS: We used 14 cell lines, including 3 isogenic pairs carrying mutant/knockout p53, to gain insight into the relationship between AXL and TP53. These included HCT116, HCT116.p53 mutant, RKO, and RKO.p53-/- lines (all from...

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Identifiers

PMID: 28596680
DOI: 10.3748/wjg.v23.i19.3440
PMCID: PMC5442080

Genes

AXL

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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